The Cognitive Performance Cost of Increased Work of Breathing


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 17-001529
    Sponsor Protocol Number: FA8650-12-D-6280

About this study

The purpose of this study is to determine the extent to which the work of breathing impacts on cognitive performance.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Physically active
  • Age 25-50 years

Exclusion Criteria:

  • History of respiratory, cardiovascular, or metabolic disease, anemia (<12 g/dL for males, <11 g/dL for females), migraines, or are pregnant
  • Subjects will not be allowed to participate if they currently smoke or have had a significant history of smoking (>5 pack yrs) 
  • Have a body mass index of ≥30 kg·m-²

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Closed for enrollment


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