A Study to Learn More About the Material Properties of the Arteries in Healthy Individuals


About this study

The purpose of this research study is to obtain knowledge of the elastic and viscous components of the material properties of the arteries in healthy individuals. All soft tissues have both elastic and viscous components, and we are trying to quantify these properties arterial vessels. The aim of the study is to evaluate if these properties are unique indicators of cardiovascular health.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:    

  • Healthy volunteers:
    • Normal anatomy of the carotid artery or the brachial artery in the upper arm  that can be visualized using ultrasound imaging
    • No history of cardiovascular disease 
    • Age between 18 and 85 
    • Body Mass Index (BMI) not greater than 30

Exclusion Criteria:   

  • Prior history of cardiovascular disease 
  • Prior history of obesity (BMI > 30) smokers 
  • Positive pregnancy test for female participants, (Pregnant women may have altered vascular function and hemodynamics due to hormonal levels and/or increased blood volume) 
  • Vulnerable populations such as prisoners

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

James Greenleaf, Ph.D.

Closed for enrollment

Contact information:

Pamela Engrav

(507) 255-6938


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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