A Study to Learn More About the Material Properties of the Arteries in Healthy Individuals


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 12-001763
    Sponsor Protocol Number: 12-001763

About this study

The purpose of this research study is to obtain knowledge of the elastic and viscous components of the material properties of the arteries in healthy individuals. All soft tissues have both elastic and viscous components, and we are trying to quantify these properties arterial vessels. The aim of the study is to evaluate if these properties are unique indicators of cardiovascular health.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:    

  • Healthy volunteers:
    • Normal anatomy of the carotid artery or the brachial artery in the upper arm  that can be visualized using ultrasound imaging
    • No history of cardiovascular disease 
    • Age between 18 and 85 
    • Body Mass Index (BMI) not greater than 30

Exclusion Criteria:   

  • Prior history of cardiovascular disease 
  • Prior history of obesity (BMI > 30) smokers 
  • Positive pregnancy test for female participants, (Pregnant women may have altered vascular function and hemodynamics due to hormonal levels and/or increased blood volume) 
  • Vulnerable populations such as prisoners

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

James Greenleaf, Ph.D.

Open for enrollment

Contact information:

Pamela Engrav



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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