Right Drug, Right Dose, Right Time – Using Genomic Data to Individualize Treatment


About this study

This research is being done to better understand how genetic information related to drug dosing and use can affect medical care of patients.

This study is asking to allow access to stored blood sample in the Mayo Clinic Biobank (IRB#08-007049) so researchers can study DNA to find out if genetic variants that play a role in how the body responds to certain drugs, primarily prescription drugs. In this study, we are interested in genetic variants that may affect whether some people:

• need a lower or higher dose of a drug

• are at an increased risk of side effects to a drug

• should avoid certain drugs

By doing this study, we are developing and improving ways to incorporate information about drug related genetic variants into the medical record. Some information about your genetic variants will be put into your medical record to guide your clinical care. Furthermore, we hope to identify new genetic variants related to how people’s bodies respond to drugs.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Enrolled in the Mayo Clinic Biobank (IRB # 08:0007049)
  2. Olmsted County or resident of a surrounding area.
  3. Assigned to receive primary care from a clinician in one of the Internal Medicine Clinics (Primary Care Internal Medicine, Family Medicine, etc.)
  4. Has had an office visit within 5 years of the date of selection
  5. Likely to be on drugs of interest in one to 3 years of date of selection
  6. Able to provide informed consent

Exclusion Criteria:

  1. Institutionalized (i.e., Federal Medical Prison)

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Suzette Bielinski, Ph.D., M.Ed.

Closed for enrollment

Contact information:

Tricia Lindstrom

(507) 284-2843


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