Nasal Epithelial Cell Culture And Responsiveness Study


About this study

The purpose of this study is to establish nasal epithelial cell culture techniques in the Allergic Disease Research Laboratory using nasal cytology brush samples from subjects with chronic rhinosinusitis and healthy subjects.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Subjects will be recruited from the medical practice and local community as those having CRS with nasal polyps as defined by the following:  
    • Requires ≥2 of the following symptoms: 
      • Anterior and/or posterior mucopurulent drainage
      • Nasal obstruction
      • Decreased sense of smell
    • Requires both
      • Endoscopy to confirm presence of bilateral polyps in middle meatus and
      • Imaging by CT with confirmation of bilateral mucosal disease. 
    • For the purpose of this study, previously performed rhinoscopy and CT imaging (within 3 years) that confirms ≥5 mm of mucosal swelling will be used. 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

John Hagan, M.D.

Contact us for the latest status

Contact information:

Kay Bachman R.N., C.C.R.C.

(507) 284-5689

More information


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