A Study of the Possibility of the Use of Translumenal Endoscopic Omental Patch for Closure of Perforated Viscus

Overview

About this study

The purpose of this study is to see if a new endoscopic approach to the repair of perforated ulcers in the stomach or the first part of the intestine is possible. Traditionally, either open operations (large single incision) or laparoscopic operations (multiple small camera-guided incisions) have been used to repair perforated ulcers.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Clinical diagnosis of a perforated viscus scheduled to undergo surgical intervention
  • Surgical candidate for endoscopic, laparoscopic, or open procedure
  • Age > 21
  • Signed informed written consent

Exclusion Criteria

  • Prior gastric or duodenal surgery
  • Prior total abdominal colectomy or transverse colectomy
  • Prior omentectomy or omental flaps
  • Known perforation site other than stomach or duodenum
  • Contra-indications for laparoscopy
  • Contraindications for endoscopy
  • Upper gastrointestinal anatomy that would preclude endoscopic therapy
  • Coagulopathy or thrombocytopenia
  • Pregnant
  • Age < 21 years
  • Prisoners
  • If found at surgery to have disease processes other than perforated peptic ulcer disease, will be asked for permission to record data for comparison

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Juliane Bingener-Casey, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

.
CLS-20314925

Mayo Clinic Footer