A Study of the Impact of Frailty on Health Outcomes following Aortic Valve Replacement


About this study

The purpose of this study is to determine what factors predict poor surgical outcomes, and the extent to which patient-centered outcomes differ between participants deemed frail and non-frail.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Men and women 65 years and older
  • Diagnosed with severe aortic stenosis who are either medically managed or having TAVR or SAVR.

Exclusion Criteria:

  • Unable to walk 15 feet with or without an assistive device

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Nathan LeBrasseur, Ph.D., M.S.

Closed for enrollment

Contact information:

Nathan LeBrasseur Ph.D., M.S.



More information


Publications are currently not available

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