A Study of Childhood Onset Narcolepsy


About this study

The purpose of this study is to evaluate the clinical presentations, polysomnographic features, treatment patterns of all children with narcolepsy in multiple CTSA (Clinical and Translational Science Award) centers.Comparison between recent cases (2009-June 30, 2012) and old cases (prior to 2009) will be performed.  To assess the role of infection and other triggering factors in early onset Narcolepsy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Age 0-18 years at diagnosis of narcolepsy
  2. Confirmed diagnosis of narcolepsy from short sleep latency less than 8 minutes and at least 2 sleep onset REM periods (SOREMP) from MSLT

Exclusion Criteria: 

  1. Subjects who have narcolepsy secondary to neurodegenerative disorders, brain tumors.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Suresh Kotagal, M.D.

Closed for enrollment

More information


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