Podocyturia in Diabetes Mellitus Type 2 and Proteinuric Glomerulonephritides

Overview

About this study

The goal of this study is to evaluate the presence of podocytes (special cells in the kidney that prevent protein loss) in the urine in patients with diabetes or glomerulonephritis (inflammation in the kidneys). Loss of podocyte in the urine may be an earlier sign of kidney injury (before protein loss) and the goal of this study is to evaluate the association between protein in the urine and podocytes in the urine.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Individuals of 18 years of age or older
  • Evaluated in the subspecialty clinics of
    • Department of Nephrology and Hypertension
      • Diabetic Nephropathy Clinic 
      • Glomerulonephritis Clinic  
    • Diabetes Clinic at the Department of Endocrinology 
  • Patients with DM type 2  
  • Patients with proteinuric glomerulonephritis

Exclusion Criteria:

  • GFR less than 20 ml/min/SA
  • Pregnancy
  • Positive urine or serum studies for monoclonal gammopathy
  • In patients with DM to have another concurrent type of glomerulonephritis
  • In patients with DM to have active hepatitis B or C

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Vesna Garovic, M.D., Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20314050

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