A Study of Measurement of Renal Viscoelastic Properties with Ultrasound

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 11-003249
    Sponsor Protocol Number: 11-003249

About this study

The purpose of this study is to obtain knowledge of the viscoelastic material properties of the kidney in healthy individuals, patients with chronic kidney disease, and patients who have received a kidney transplant. The aim of the study is to evaluate if these properties are unique indicators of renal health.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:    

  • Chronic kidney patient subjects:
    • Patients with a positive diagnosis of chronic kidney disease with an estimated glomerular filtration rate of less than 90 and an albumin/creatinine ration of greater than 30 mg/g
    • Age between 21 and 85 
    • Able to reliably comprehend and perform simple verbal commands and written consent 
    • Body Mass Index (BMI) not greater than 45. These patients will be categorized into different stages (1-5) of chronic kidney disease based on estimated glomerular filtration rate according to the K/DOQI guidelines.
  • Kidney transplant patient subjects:
    • Patients who have received a kidney transplant 
    • Age between 21 and 85 
    • Able to reliably comprehend and perform simple verbal commands and written consent 
    • Body Mass Index (BMI) not greater than 45
  • Kidney transplant donors:
    • Normal anatomy and no history of kidney disease and donating a kidney 
    • Age between 21 and 85 
    • Body Mass Index (BMI) not greater than 45

Exclusion Criteria:   

  • Chronic kidney patient subjects:
    • Patients with cystic kidney disease 
    • Patients undergoing dialysis treatment 
    • Vulnerable populations such as prisoners
  • Kidney transplant patient subjects:
    • Patients with cystic kidney disease 
    • Patients undergoing dialysis treatment 
    • Vulnerable populations such as prisoners
  • Kidney donors:
    • Prior history of kidney disease 
    • Vulnerable populations such as prisoners

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Matthew Urban, Ph.D.

Open for enrollment

Contact information:

Maria Stevens

(507)422-5992

Stevens.Maria@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20313911

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