Evaluation of Perivalvular Leak Repair in Adults


About this study

The aim of this study is to determine that percutaneous repair of paravavular defect has improved clinical outcomes, survival, reduced the incidence of hemolysis related to the paravalvular leak, and that percutaneous intervention has reduced the overall need for surgical intervention.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Anyone 18 years and older who have had a percutaneous repair technique for device closure of paravalvular leak.

Exclusion Criteria:

  • Anyone < 18 years of age.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Charanjit Rihal, M.D.

Closed for enrollment

Contact information:

Diana Albers B.S.

(507) 255-6884


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