Matched Serum and Cerebrospinal Fluid Disease Repository


About this study

The aim is to establish a repository consisting of clinical information, radiological data, serum, peripheral blood lymphocytes, plasma, cerebrospinal fluid (CSF), and tissue specimens collected prospectively from patients with CNS diseases and controls.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Subjects:
    • Disease of the central nervous system consideredto be inflammatory in nature
  • Controls:
    • Patients who are attending for lumbar puncture for therapy or diagnosis of normal pressure hydrocephalus or another condition that requires a lumbar puncture


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Sean Pittock, M.D.

Closed for enrollment

More information


Publications are currently not available

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