A Study of the Frequency and Severity of Emotional and Cognitive Symptoms Following ICU Care


About this study

The purpose of this study is to measure the frequency and severity of posttraumatic stress symptoms, depressive symptoms, anxiety symptoms, and cognitive impairment following dismissal from the ICU and three months later. This study also seeks to identify which of the multiple ICUs at Mayo Clinic yields the highest incidence of post-intensive care syndrome so that a future study designed to provide a therapeutic intervention can be implemented in those areas with the greatest potential.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Age >18
  • Requires ICU stay > 48 hours

Exclusion Criteria

  • Admitted for suicide attempt
  • Known prior cognitive impairment or dementia
  • Known prior diagnosis of posttraumatic stress disorder
  • Life expectancy < 3 months
  • Non-English speaking
  • Delirium
  • Severe current cognitive impairment

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Lioudmila Karnatovskaia, M.D.

Closed for enrollment

Contact information:

No Contact

More information


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