Collection of Surgical Waste Synovium Tissue and Waste Synovial Fluid from Elective Joint Aspirations


About this study

The purpose of this study is to see if the inflammation in early stage arthritis can be cessated by changing synoviocyte-macrophage interactions in a way that macrophages do not get activated.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • knee / hip osteoarthritis, ACL tear, meniscus tear

Exclusion Criteria:

  • Patients who have previously received immune-suppressive therapies not including NSAIDs and acetaminophen.
  • Vulnerable patient populations (e.g., pregnant women, children, adults lacking capacity to consent, prisoners, non-native English speakers.
  • Recent infection (<1 month), including the common cold
  • History of cancer
  • Autoimmune diseases

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Wenchun Qu, M.D., M.S., Ph.D.

Closed for enrollment

More information


Publications are currently not available

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