A Study of a Computer-Aided Analysis Tool for the Assessment of Pulmonary Fibrosis Treatment


About this study

The purpose of this study is to determine the effectiveness of a new computer-aided analysis tool in identifying treatment response in idiopathic pulmonary fibrosis. Computer-Aided Lung Informatics for Pathology Evaluation and Ratings (CALIPER) is  an image analysis tool for characterizing and measuring mixed parenchymal diseases such as emphysema and interstitial lung diseases and has been shown to correlate with idiopathic pulmonary fibrosis mortality.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients with suspected or diagnosed pulmonary fibrosis.
  • Age ≥ 18 years.
  • Patients who planning to undergo treatment with at least one anti-fibrotic agent OR patients who have been undergoing treatment with one anti-fibrotic for up to six months.
  • Subjects must be able to understand and be willing to sign the written informed consent form.

Exclusion Criteria:

  • Diagnosis of secondary pulmonary fibrosis.
  • Pregnancy.
  • Inability to comply with the protocol and/or not willing or not available for follow-up assessments.
  • Any condition which, in the investigator’s opinion, makes the subject unsuitable for trial participation.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Chi Wan Koo, M.D.

Closed for enrollment

Contact information:

Pulmonary Research Study Coordinator

(800) 753-1606

More information


Publications are currently not available

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