Spontaneous Coronary Artery Dissection (SCAD):Utility of Echocardiography including Contrast and Strain Imaging


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 15-006436
    Sponsor Protocol Number: 15-006436

About this study

The purpose of this study is to perform and analyze standard transthoracic echocardiography with contrast and strain imaging in 80 consecutive patients seen in the Mayo Clinic Spontaneous Coronary Artery Dissection (SCAD) Clinic and interpret any prior pre- or post-SCAD echocardiogram studies for comparison.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Clinical diagnosis (by history and diagnostic angiographic features) ofspontaneous coronary artery dissection (SCAD )

Exclusion Criteria:

  • Patients with any clinically unstable cardiac condition (within 24 hours of) Lumason administration
  • Known or suspected right-to-left, bi-directional,or transient right-to-left cardiac shunts
  • History of hypersensitivity reactions to sulfurhexafluoride lipid microsphere components or to any of the inactive ingredients in Lumason
  • Lack of visualization of the left ventricle at baseline study
  • Pregnancy or lactation.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Marysia Tweet, M.D.

Open for enrollment

Contact information:

Jill Boyum




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