Prospective Study of Adrenal Disorders: Clinical Registry, Imaging Analysis and Biomaterial Collection


About this study

The purpose of this research is to follow people with adrenal disorders in order to make conclusions about the natural history of a particular adrenal disease as well as effect of various therapies and interventions decided on by you and your medical team. In addition, we will collect biomaterial from you at times you are being evaluated which will be used to discover novel biomarkers which can potentially improve the accuracy of current diagnostic tests and affect the management of patients with adrenal disorders. We will also include a control group (without known adrenal disease) to compare to the volunteers with adrenal disorders.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:            

  • Patients with:

    • adrenal mass of any etiology

    • steroidogenesis defect ( examples: 21OH congenital hyperplasia, 11 beta congenital hyperplasia)

    • primary or secondary adrenal insufficiency

    • Cushing’s syndrome due to pituitary or ectopic ACTH production

    • Inadequate glucocorticoid, mineralocorticoid or androgen axis of unknown etiology

    • Healthy individuals

    • Patients seen for problems other than mentioned above and willing to contribute biomaterial

  • Age 18-99 years

    Exclusion Criteria:           

  • Age <18 years


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Irina Bancos, M.D.

Open for enrollment

Contact information:

Vanessa Fell

(507) 266-6068

More information


Publications are currently not available

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