Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion


About this study

The overall purpose is to study how a variety of technological approaches in Magnetic resonance imaging (MRI) can be used to provide improved performance contrast-enhanced MR imaging as used for angiography and perfusion.  These include but are not limited to improvements in: (i) receiver coils; (ii) pulse sequences for data acquisition; (iii) methods for image reconstruction; (iv) algorithms for deriving MRI-based quantitative parameters and biomarkers.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults

Exclusion Criteria: 

  • Standard exclusion criteria for clinical MRI; e.g. cardiac pacemaker, claustrophobia, an implanted device that has been determined to be MR conditional at 1.5T but not at 3T, anticipated considerable susceptibility artifact from hip prosthesis, etc.
  • previous rectal surgery which may preclude tolerance of an endorectal coil

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Stephen Riederer, Ph.D.

Open for enrollment

Contact information:

Kathy Brown

(507) 538-1321

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Akira Kawashima, M.D., Ph.D.

Closed for enrollment

More information


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