Pain Severity and Pain Interference Outcomes following Percutaneous MRI-Guided Laser Ablation and Cryoablation of Painful Peripheral, Soft Tissue Vascular Anomali

Overview

About this study

The purpose of this study is to determine if MRI-guided laser ablation and cryoablation result in significant improvements in both pain severity and pain interference measures at intermediate-term follow-up in patients with painful, soft-tissue vascular anomalies. The study will also test the hypothesis that immediate loss of intrinsic vascular anomaly T2 signal is an imaging biomarker to predict decreased pain and VA volume following MRI-guided laser ablation and cryoablation in patients with painful, soft-tissue vascular anomalies. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion Criteria:

  • Adult patients with an imaging diagnosis of a vascular anomaly and vascular anomaly associated pain (Pain score of 4 or higher on a scale of 0–10 for the question, “Please rate your pain by circling the one number that best describes your worst pain over the past 24 hours”) referred for clinically indicated MRI-guided percutaneous laser ablation or cryoablation using FDA approved ablation devices who consent to study participation.

Exclusion Criteria: 

  • Adult patients with an imaging diagnosis of a vascular anomaly and vascular anomaly associated pain (Pain score of 3 or less on a scale of 0–10 for the question, “Please rate your pain by circling the one number that best describes your worst pain over the past 24 hours”) referred for clinically indicated MRI-guided percutaneous laser ablation or cryoablation using FDA approved ablation devices who consent to study participation.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

David Woodrum, M.D., Ph.D.

Open for enrollment

Contact information:

Desirae Howe-Clayton

(507)255-0111

Howe.Desirae@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20306801

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