Counter-Regulation and Postprandial Symptoms in Patients who have Undergone Auto-Islet Transplantation


About this study

The purpose of this study is to determine the mechanism(s) underlying symptoms of hypoglycemia that are experienced by patients after auto-islet transplantation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients who have undergone islet transplantation with islets placed within the liver and (in some cases) the peritoneal cavity
  • Control subjects will be recruited from Olmsted County residents and surrounding counties, who have previously indicated a willingness to participate in research

Exclusion Criteria:

  • Age < 18
  • Age >72
  • For female subjects: positive pregnancy test at the time of enrollment or study
  • Previous treatment with thiazolidinediones

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Adrian Vella, M.D.

Closed for enrollment

More information


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