A Study of the Quality of Life after Surgery for Recurrent Rectal Cancer


About this study

The purpose of this study is to measure the quality and quantity of the lifespan in patients who have locally recurrent rectal cancer. It will compare survival rates and quality of life of those who have surgery to those who do not have surgery. It also aims to compare certain other factors, such as whether clear resection margins (i.e. “R0 margins” which are when no evidence of the tumour is found in the biopsy) were achieved and the influence of chemotherapy and radiotherapy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Has an isolated locally recurrent adenocarcinoma of the rectum or recto-sigmoid
  • Considered for radical resection with or without perioperative chemoradiation
  • Age 18 years or older
  • Able to consent to participate

Exclusion Criteria

  • No adenocarcinoma
  • Has primary (not recurrent) cancer
  • Has non-resectable metastatic disease

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Eric Dozois, M.D.

Open for enrollment

Contact information:

Eric Dozois M.D.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


Mayo Clinic Footer