Clinical Protocol Development on a PET/MR System


About this study

The objective of this pilot research protocol is to evaluate the quality of PET from the SIGNA PET/MR system and to compare the quantitative accuracy of PET images from the PET/MR system to PET images from a standard PET/CT system. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • Patients 18 to 100 years of age
  • Patients who are scheduled for a clinically indicated F-18 FDG PET/CT study
  • Patients who are able and willing to sign the informed consent will be enrolled
  • Patients at high risk for multiple sites of F-18 FDG avid abnormalities based on prior clinical or radiologic evaluation or those who demonstrate multiple sites of abnormal FDG uptake on their clinical PET/CT scan will be selected for participation.In this way patients will be enrolled who provide the highest likelihood of having multiple FDG avid sites to serve as evaluable comparisons between the standard PET/CT scan and the PET/MR scan.
  • Patients who have a BMI of at least 18.5 kg/m2
  • Patients who pass standard clinical MRI screening procedures

Eligibility Criteria:

  • Patients who are unable to lay quietly for an additional 60 minutes of imaging
  • Patients who are claustrophobic
  • Patients who weigh more than 350 lbs or whose body habitus precludes them from participation

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Ming Yang, M.D.

Open for enrollment

Contact information:

Marilyn Wood CCRP


More information


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