A Study to Understand the Connections Between Brain Functioning and Speech in Patients with ALS


About this study

The purpose of this study is to create a collection of speech samples to provide researchers with large amounts of data needed to obtain conclusive insights into the links between brain functioning and speech.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • A diagnosis of ALS of either bulbar or spinal forms
  • Speech production that is intelligible at the phrase level
  • Controls with normal speech production

Exclusion Criteria

  • Dementia that precludes voluntary participation
  • Anarthria

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Julie Stierwalt, Ph.D.

Closed for enrollment

More information


Publications are currently not available

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