A Study of Surgical Management of Postprandial Hyperinsulinemic Hypoglycemia after Roux-en-Y Gastric Bypass Surgery


About this study

The purpose of this study is to understand outcomes from patients who have undergone roux-en-y gastric bypass and developed postprandial hypoglycemia which required surgery.   



Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age >18 years
  • History of Roux-en-Y gastric bypass (RYGB) or other bariatric surgery
  • Subjects who developed the following at any point after RYGB or any bariatric surgery-
    • Symptoms of hypoglycemia AND/OR
    • Fasting blood glucose < 60 mg/dl AND/OR
    • Resolution of symptoms with administration of a glucose source AND/OR
    • Elevated serum insulin or c-peptide levels
  • Post RYGB patients who underwent surgical procedure in attempt to cure the problems described in point 3 above

Exclusion Criteria:

  • Patients with history of surgical procedure other than RYGB

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Travis McKenzie, M.D.

Closed for enrollment

More information


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