A Study of Oxygen Binding to Hemoglobin During Exercise and Hypoxia in Humans.


About this study

The purpose of this study is to determine how oxygen binding to hemoglobin affects gas exchange during exercise in humans. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Healthy male and female non-smoking participants
  • 18 years old or older
  • no significant metabolic, cardiovascular or neurologic disease and no contraindications to exercise.  

Exclusion Criteria:

  • Medications that might influence the cardiovascular or respiratory responses to exercise will be excluded (e.g. beta blockers and some other antihypertensives along with anti-asthma drugs). 

All inclusion/exclusion criteria are at the discretion of the principal investigator.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

More information


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