A Study to Measure Blood Vessel Health in Non-Pregnant Women


About this study

This study will allow us to determine normal values for the health of this gel-like layer in non-pregnant women. We will also determine whether values vary from day to day, in the same person. Normal responses from this study will be compared with data obtained in other studies (for example, studies of women who had the pregnancy complication preeclampsia, or women who have other risk factors for heart disease). This will help us to determine whether the glycocalyx contributes to the risk of preeclampsia and heart disease in women with different risk factors.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Non-pregnant women
  • Between 18 and 40 years of age
  • Are not taking any regular medications 
  • Non-smokers
  • Generally healthy

Exclusion Criteria:

  • Pre-existing hypertension
  • Diabetes
  • Cardiovascular or renal disease
  • Systemic inflammatory disorders
  • Other health problems

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Vesna Garovic, M.D., Ph.D.

Open for enrollment

Contact information:

Justin Patri B.S.

(507) 293-3732


More information


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