A Study of Information Provided by Cardiopulmonary Exercise Testing When Evaluating Patients with Aortic Stenosis


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 15-007706
    Sponsor Protocol Number: 15-007706

About this study

The purpose of this study is to find if cardiopulmonary exercise testing data will provide any predictive information in evaluating patients with aortic stenosis for severity, symptoms and surgical risk.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Diagnosis of aortic stenosis
  • Had cardiopulmonary exercise testing between November of 2007 and April of 2014
  • An aortic valve area < 1.5 cm2 and some question of the need for or timing of aortic valve replacement identified in the clinical notes
  • Coronary artery disease or atrial fibrillation will not be excluded

Exclusion Criteria

  • Concomitant mitral valve disease of sufficient severity to potentially indicate a two-valve operation
  • Other life-limiting diseases 
  • Inability to perform the exercise of the cardiopulmonary exercise testing

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Thomas Allison, Ph.D.

Closed for enrollment

Contact information:

Thomas Allison Ph.D.



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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