A Study of the Large-scale Organization of the Brain and Producing Measurable Change with Intervention


About this study

The purpose of this study is to develop improved assessments and mappings of the large scale organization of the brain, and look at the possibilities of producing measurable change with non-drug intervention.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Cognitively normal subjects
  • Atleast 18 years of age
  • At baseline state of mental and physical health


Exclusion Criteria 

  • Age less than 18 years
  • Confounding CNS pathology that may theoretically interfere with data processing or intrinsic resting state networks, e.g.
    • Large stroke
    • High grade glioma
    • Neurodegenerative illness 
    • Significant neuropsychiatric disorder
  • Contraindication to MRI, e.g.
    • Metallic fragments near eye, brain, or spinal cord
    • Magnetically activated implanted devices
    • Claustrophobia
  • Pregnancy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

David Jones, M.D.

Closed for enrollment

Contact information:

David Jones M.D.



More information


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