A Study to Evaluate the Combining of Endoscopic Ultrasound Guided Liver Biopsy and Stomach Balloon Placement for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease and Obesity

Overview

About this study

The purpose of this study is to evaluate the usefulness of combining a core liver biopsy guided by endoscopic ultrasound and stomach balloon placement by endoscope for the diagnosis and treatment of fatty liver disease and obesity.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Nonalcoholic steatohepatitis patients with evidence of early fibrosis on MRE-Hepatogram
  • Referred for an intragastric balloon placement for weight loss

Exclusion Criteria

  • Age ≤ 21 or ≥ 70 years
  • Pregnancy, plan for pregnancy or lactating
  • Previous history of gastric surgery
  • Current or recent (within 6 months) gastric or duodenal ulcers
  • Gastroparesis
  • Liver cirrhosis
  • Coagulopathy or active use of anticoagulation
  • Inability to provide a written informed consent

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Barham Abu Dayyeh, M.D., M.P.H.

Closed for enrollment

Contact information:

Monika Rizk Salib

(507)266-0516

Salib.Monika@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20260180

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