A Study of Continuous Simultaneous Recording of Skin Sympathetic Nerve Activity and Electrocardiography for Predicting the Sudden Start of Ventricular Arrhythmia Events and Response to Treatment


About this study

The purpose of this study is to use a noninvasive method of recording together skin sympathetic nerve activity and electrocardiogram (ECG) to assess the sympathetic activity of the heart. The potential use of this is in the prediction of ventricular arrhymia and identifying the response to resynchronization therapy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • ≥ 18 years of age
  • Have ischemic or dilated cardiomyopathy and develop sustained ventricular tachyarrhythmias that were documented within 6 months before study enrollment
  • Meet clinical indication for CRT-D or CRT-P implantation (aim 2)
  • Willing to sign the consent

Exclusion Criteria

  • Pregnant women

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Yongmei Cha, M.D.

Closed for enrollment

More information


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