A Study of the Effects of Initiating Assisted Ventilation During a Period of Delayed Cord Clamping for Extremely Preterm Infants

Overview

About this study

The purpose of this study is to determine whether initiating breathing assistance prior to clamping the umbilical cord influences the occurrence of intraventricular (brain) hemorrhage in extremely preterm infants, compared to the standard care of starting ventilation assistance after cord clamping.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • 23 0/7 - 28 6/7 weeks gestation at delivery

Exclusion Criteria

  • Life-threatening condition of fetus (e.g. severe hydrops, lethal chromosomal abnormality, severe congenital malformation)
  • Suspected severe fetal anemia
  • Monochorionic or monoamniotic twins
  • Multiple gestation greater than twins
  • Decision made for comfort care only
  • Medical emergency necessitating emergency delivery (e.g. complete placental abruption)
  • Obstetrician or Neonatology concern for inappropriateness of the study intervention based on maternal or fetal factors

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jennifer Fang, M.D.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Lavonne Liedl R.R.T., L.R.T.

(507)255-1828

liedl.Lavonne@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20238954

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