A Study to Collect and Correlate the Data from Multiple Risk Assessments for Heart Toxicity in Patients Receiving Chemotherapy for Breast Cancer


About this study

The purpose of this study is to collect and correlate the data from various cardiovascular risk asessments to successfully measure the risk of heart toxicity in patients receiving chemotherapy for breast cancer.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Female
  • ≥ 18 years of age
  • Group 1
    • All  consented under IRB 1815-04 and agreed to the cardiac portion
    • Have data that includes information such as echocardiograms (pre-treatment, during treatment and at end of treatment), endoPATs, and bloods collected as part of the cardiac study under this IRB
    • Letter of support obtained from Dr. Olson for this information
  • Group 2
    • Newly diagnosed with HER-2 positive breast cancer
    • Seen at Mayo Clinic Rochester
    • Is planning to undergo anti-HER2 therapy with or without anthracycline within the Mayo Clinic Health System
      • May have treatment at an outside facility if they are willing to return to Mayo Clinic for their cardiac monitoring
    • Meet our inclusion criteria

Exclusion Criteria 

  • Left ventricular ejection fraction < 50%

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Joerg Herrmann, M.D.

Closed for enrollment

Contact information:

Lisa Littlefield



More information


Publications are currently not available

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