A Study of Pre-Surgery Inspiratory Muscle Training for Patients who will have Surgery on Their Esophagus


About this study

The purpose of this study is to get definite evidence for the effectiveness of a short preoperative inspiratory muscle training protocol on the level of sickness and recovery of patients who are having the surgical removal of a portion of the esophagus.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.


Inclusion Criteria

  • Diagnosed with esophageal cancer 
  • Scheduled for esophageal resection at the Mayo Clinic Rochester with gastric conduit reconstruction
  • Cognitively capable to understand and perform a preoperative program
  • Able to follow the intervention program for at least 2 weeks before surgery (surgery is usually scheduled 4 to 12 weeks after radiation)
  • Willing to sign the informed consent form

Exclusion Criteria

  • Unable to communicate in the English language
  • Participating in a conflicting trial concerning esophageal resection

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Roberto Benzo, M.D.

Closed for enrollment

More information


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