A Study Comparing Sodium Nitroprusside and Nitroglycerin to Determine the Dose of Each Needed to get the Same Response


About this study

The purpose of this study is to find the doses needed of sodium nitroprusside and nitroglycerin to get an equal response, assessed by forearm blood flow.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Healthy males and females
  • Between 18-50 years old
  • Non-smokers
  • Have no current cardiac, renal, vascular, pulmonary, endocrine, or neurological disease


Exclusion Criteria

  • Pregnancy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

More information


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