Bathing Additives in Pediatric Atopic Dermatitis


About this study

The current clinical guidelines for management of atopic dermatitis now recommend bleach baths. This requires simply the addition of regular household bleach to twice-weekly baths. At the Mayo Clinic, dilute acetic acid (vinegar) has been recommended for decades in wet wraps to treat patients hospitalized for their atopic dermatitis. However, this practice has not been widely adopted in the pediatric dermatology community. Will the use of dilute acetic acid (vinegar) in twice weekly baths help manage atopic dermatitis in pediatric patients as well as, or better than, the current accepted guidelines?

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Patients from 6 months to 17 years of age
  2. Currently residing in US.
  3. Follow up visits at 1 month, 3 months and 6 months after initiation of treatment in study (Figure 1).
  4. Last follow-up at 1 year in clinic or via written mailed-out survey.
  5. Diagnosis of atopic dermatitis AND
    1. Have active signs of bacterial skin infection OR
    2. Any documented suspected history of bacterial skin infection (weeping, crusting, and/or pustules on exam), OR
    3. Prescription for oral antibiotics for skin infection in the past 6 months from any provider). OR
    4. Have been prescribed bleach baths as part of an atopic dermatitis skin care regimen.

Exclusion Criteria:

  1. Superficial skin infection without diagnosis of atopic dermatitis
  2. Lack of in-clinic follow up assessment at 6 months

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Megha Tollefson, M.D.

Closed for enrollment

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