A Study of Using Proton Beam Therapy Which Spares Mucosal Tissue Following the Removal of Oropharyngeal Tumors

Overview

About this study

The purpose of this study is to evaluate the clinical outcomes of lower intensity (mucosal tissue sparing) proton beam therapy after the surgical removal of oropharyngeal tumors in cancer patients who have a favorable level of risk.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Criteria:

  • Resection of oropharyngeal tumor by transoral surgery using frozen section margin analysis resulting in a negative margin resection
  • No extensive perineural invasion after review by head and neck pathologist
  • No lymphovascular invasion after review by head and neck pathologist
  • Pathologic stage T1-2 N1-3 M0 disease

Exclusion Criteria:

  • T3 or T4 primary stage disease
  • Prior randomization to an investigational head and neck protocol

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Samir Patel, M.D.

Contact us for the latest status

Contact information:

Heather Young CCRP

(480)301-4629

Young.Heather@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

Daniel Ma, M.D.

Contact us for the latest status

Contact information:

Heather Young CCRP

(480)301-4629

Young.Heather@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20200701

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