A Study of Blood Clotting Response in Patients with a Traumatic Injury

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 14-008481
    Sponsor Protocol Number: 14-008481

About this study

The purpose of this study is to look at the blood’s clotting response in people who have suffered a traumatic injury and compare it with non-injured people.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Trauma patients who arrive to Mayo Clinic Hospital - Saint Marys Emergency Deparment and are classified as Level Red and Yellow activations.
  • Male and female patients 18 years of age or older (no upper age limit).
  • Blunt and/or penetrating traumatic injuries.

Exclusion Criteria:

  • Are on therapeutic anticoagulation, to include Coumadin/Pradaxa or antiplatelet agents (excluding Plavix, aspirin or ibuprofen).
  • Have preexisting coagulopathy (cirrhosis and inherited clotting disorders including Hemophilia A & B, Factor IX, Factor XI deficiencies).
  • Patients greater than 12 hours from time of injury.
  • Have history of known malignancy (no clinical evidence within 3 months).
  • Active diagnosis of sepsis at the time of injury.
  • Renal failure on dialysis.
  • Patients with thermal injuries ( not including “road rashes”).
  • Patients on high dose steroids or autoimmune medications.
  • Patients who have experienced traumatic injuries within the past 1 year.
  • Known pPregnancy.
  • Prisoners.
  • Have a preexisting medical condition that, in the judgment of the investigator, would preclude participation in this study.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Myung Park, M.D., M.S.

Open for enrollment

Contact information:

Amy Headlee CCRP

(507)422-0406

Headlee.Amy@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20199968

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