A Study of Blood Clotting Response in Patients with a Traumatic Injury

Overview

About this study

The purpose of this study is to look at the blood’s clotting response in people who have suffered a traumatic injury and compare it with non-injured people.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Trauma patients who arrive to Mayo Clinic Hospital - Saint Marys Emergency Deparment and are classified as Level Red and Yellow activations.
  • Male and female patients 18 years of age or older (no upper age limit).
  • Blunt and/or penetrating traumatic injuries.

Exclusion Criteria:

  • Are on therapeutic anticoagulation, to include Coumadin/Pradaxa or antiplatelet agents (excluding Plavix, aspirin or ibuprofen).
  • Have preexisting coagulopathy (cirrhosis and inherited clotting disorders including Hemophilia A & B, Factor IX, Factor XI deficiencies).
  • Patients greater than 12 hours from time of injury.
  • Have history of known malignancy (no clinical evidence within 3 months).
  • Active diagnosis of sepsis at the time of injury.
  • Renal failure on dialysis.
  • Patients with thermal injuries ( not including “road rashes”).
  • Patients on high dose steroids or autoimmune medications.
  • Patients who have experienced traumatic injuries within the past 1 year.
  • Known pregnancy.
  • Prisoners.
  • Have a preexisting medical condition that, in the judgment of the investigator, would preclude participation in this study.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Myung Park, M.D., M.S.

Open for enrollment

Contact information:

Amy Headlee CCRP

(507)422-0406

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20199968

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