Gut Permeability Assessment in Celiac and Gluten Sensitive Children


About this study

This study will assess the effect of gluten on gut barrier function. Investigators at the Mayo Clinic have developed a new gut permeability test using rhamnose (sugar & water solution), and are hoping to prove its effectiveness in a clinical setting.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • High Risk group
    • Sibling with a confirmed diagnosis of celiac disease
    • No history Celiac disease or any other bowel disease
  • Non-Celiac Gluten Sensitivity group
    • Self-diagnosis of gluten sensitivity
    • No history of celiac disease or other bowel disease
  • Healthy group
    • Absence of celiac disease or any other bowel disease
    • No sensitivity to gluten

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Imad Absah, M.D.

Closed for enrollment

More information


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