A Study of the Role of the Pericardium in Cardiac Arrhythmias


About this study

This study is being done to understand whether the fluid that is normally in the pericardial space (2-3 ounces) that surrounds the heart contributes to  arrhythmias.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Subjects with ventricular tachycardia that require an epicardial ablation approach.
  • Subjects with atrial fibrillation who require the deployment of left atrial appendage occluder device (LARIAT).
  • Subjects with frequent ventricular ectopic activities that require an epicardial ablation approach.
  • Subjects with coronary artery disease undergoing CABG with a history of atrial fibrillation.

Exclusion Criteria: 

  • Subjects not requiring one of the above ablative or surgical procedures.
  • Subjects not willing to provide consent.
  • Patients with concomitant mitral valvular heart disease, or congenital heart disease.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Hon-Chi Lee, M.D., Ph.D.

Open for enrollment

Contact information:

Kristi Monahan B.S.

(507) 255-6676


More information


Publications are currently not available

Mayo Clinic Footer