The Role of Microbiota in the Pathogenesis of Pouchitis


About this study

The purpose of this study is to learn more about the bacteria that live in the small and large intestine and the role that these bacteria play in causing inflammation in the gastrointestinal tract.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion criteria:

A patient may be considered for study participation if all of the following apply:

  1. Age greater than or equal to 18 years
  2. Confirmed diagnosis of ulcerative colitis or familial adenomatous polyposis
  3. Subjects who have undergone proctocolectomy  with ileal pouch anal anastomosis and are scheduled for, or have had takedown of ileostomy at any time
  4. The patient is willing and able to sign the written, informed consent document

Exclusion criteria:

Patients will be excluded from the study if one or more of the following apply:

  1. Female patients who are pregnant
  2. The patient appears to be uncooperative or not dependable for any reason
  3. Patients unable to give informed consent

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Laura Raffals, M.D.

Closed for enrollment

Contact information:

Shawn Haren B.S., C.C.R.C.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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