A Study of the Effects of Menopause and Exercise on Blood Flow in Healthy Women


About this study

The purpose of this study is to see if age, sex hormones and regular exercise impact blood flow in healthy women.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • young premenopausal women ages of 18 and 35 years old or non-surgically induced post-menopausal women ages 45-75
  • non-smokers.
  • premenopausal subjects will undergo a urine pregnancy test, must be negative to participate


Exclusion Criteria

  • Any history or evidence of hepatic, renal, or hematological disease
  • Peripheral vascular disease
  • Stroke/neurovascular disease
  • Diabetes
  • Dyslipoproteinemia
  • Uncontrolled hypertension
  • Lung disease, or arthritis affecting ability to exercise
  • A body mass index >30 kg/m2
  • If taking medication that alters autonomic or vascular function (e.g., tricyclic antidepressants, α-blockers, β-blockers, etc.)
  • Subjects who are breastfeeding will be excluded.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

More information


Publications are currently not available

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