A Study of the Measurement of Blood Sugar Variation in Type 1 Diabetic Children, and Finding the Causes

Overview

About this study

The purpose of this study is to use multiple devices to measure blood sugar changes and the reasons for these changes in healthy and diabetic children.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Type 1 diabetes diagnosed clinically at least 1 year prior to enrollment
    • Males must be Tanner stage 4-5
    • Females will have attained menarche 
    • currently on CSII with HbA1c <10 % 
    • physically active based on self-report 
    • no eating disorder 
    • high likelihood of compliance with protocol and completion of study 
    • absence of an intercurrent illness during the study period
  • Healthy children will need to meet the above criteria except for diabetes diagnosis and HbA1c criteria.
    • Male participants will be Tanner stage 4 or 5 
    • Females would have attained menarche
    • Healthy subjects will be recruited from the general population and can be siblings of type 1 diabetics

 

 

Exclusion Criteria

  • Factors confounding insulin action such as abnormal kidney and liver function, celiac disease and colitis 
  • Eating disorder 
  • Simultaneous involvement in another research study that would confound the current study
  • Inability or unwillingness of individual or legal guardian/representative to give written informed consent
  • Pregnancy
  • Any other condition that in the opinion of the study team would be concerning

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Yogish Kudva, M.B.B.S.

Closed for enrollment

Contact information:

Shelly McCrady-Spitzer M.S.

(507)255-5916

McCradySpitzer.Shelly@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20151752

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