Dominantly Inherited Alzheimer Network (DIAN)


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Jacksonville, Florida: 12-001466
    NCT ID: NCT00869817
    Sponsor Protocol Number: ADC-034

About this study

The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Age 18 or older
  • Child of an individual with a known mutation in a pedigree with autosomal dominant Alzheimer's disease
  • Cognitively normal, or if demented, does not require nursing home level care
  • Fluent in English or Spanish at the 6th grade level
  • Has someone who is not a child of the affected parent who can serve as an informant for the study

Exclusion Criteria:

  • Under age 18
  • Medical or psychiatric illness that would interfere in completing initial and follow-up visits
  • Requires nursing home level care
  • Has no one who can serve as a study informant

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Neill Graff-Radford, M.D.

Open for enrollment

Contact information:

Sochenda Chea



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