A Study of Nighttime Blood Sugar Control Patterns in Type 2 Diabetes


About this study

The purpose of this study is to understand nighttime glucose regulation in humans and find if the pattern is different in people with Type 2 diabetes

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.


Inclusion Criteria

  • 30 subjects per group and may need to screen up to 120
  • 30-75 years of age
  • body mass index (BMI) of 27-40 kg/m2
  • Groups will be matched for age, sex and BMI
  • The ADA criteria for fasting glucose will be applied
  • Type 2 Diabetes subjects on lifestyle treatment, with or without combination therapy with metformin and sulphonylurea will have an HbA1c of ≤ 10.%

Exclusion Criteria

  • Diabetics on insulin, glucagon-like peptide-1 based therapies or thiazolidinediones
  • Type 2 Diabetic subjects with microvascular or macrovascular complications (apart from mild background retinopathy)
  • any forms of sleep disorder identified during the screening process.  

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Kelly Dunagan, R.N.

Closed for enrollment

More information


Publications are currently not available

Mayo Clinic Footer