Sensorimotor Dysfunction in Achalasia


About this study

This study is being done to assess the esophageal muscle (swallowing tube) in patients with and without achalasia to further understand and help direct the treatment for patients with achalasia.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Criteria:

  • Adults ages 18-90
  • Patients with achalasia, defined by an esophageal manometry study consistent with the diagnosis

Exclusion Criteria:

  • Patients with EGD or esophagram findings suggestive of pseudoachalasia
  • Previous history of pneumatic dilation, Heller myotomy, or botulinum toxin injection to the distal esophagus
  • Esophageal diameter greater than 6 cm
  • Previous history of upper gastrointestinal surgery
  • Medical conditions such as severe heart or lung disease that preclude safe performance barostat
  • Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Karthik Ravi, M.D.

Closed for enrollment

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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