Use of a Collagen Membrane for Soft Tissue Grafting


About this study

Is PriMatrix wound dressing capable of regenerating gum tissue inside the mouth?

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Must have one to three consecutive teeth with recession and less than 1 mm of keratinized gingiva

Exclusion Criteria:

  • Asthma
  • Pregnancy
  • Uncontrolled diabetes
  • Use of continuous positive airway pressure (CPAP) machine for sleep apnea
  • Oral appliances (removable partial dentures, braces, mandibular advancement, bruxism splints, etc.)
  • Tobacco use
  • Immunocompromised individual

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Daniel Assad, D.D.S.

Closed for enrollment

More information


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