Is Our Microbiome a Predictor of Cardiac Risk


About this study

The purpose of this study is to compare the fecal microbiota of patients with mild, moderate and severe Coronary Artery Disease (CAD) by collecting stool and blood samples from patients undergoing coronary angiograms.


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Anyone undergoing cardiac catheterization for suspected coronary artery disease over age 18.

Exclusion Criteria:

  • Patients currently on long-term antibiotics who cannot stop them for at least 2 weeks prior to providing a stool sample.
  • Patients on chronic laxatives who cannot stop for at least 24 hours prior to stool collection.
  • Patients who are unable to provide a stool sample to Mayo clinic within 24 hours of collection via FedEx overnight mail. (i.e., people overseas who are unable to provide a sample before leaving the USA).

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Amir Lerman, M.D.

Open for enrollment

Contact information:

Robert McBane

(507) 293-1433

More information


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