Ultrasound Research Center

Below are current clinical trials.

11 studies in Ultrasound Research Center
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. A Study to Determine the Feasibility of Doppler Ultrasound of Large Arterial Systems of the Brain as Vascular Involvement Markers in Presbyacusis and Presbyvestibulopathy

   Jacksonville, Fla.

   The purpose of this study is to benchmark the feasibility of carotid artery biomechanical analysis and vertebral-basilar Transcranial Doppler (TCD) as markers of vascular involvement in presbyacusis and presbyvestibulopathy.

2. A Study of Two-Dimensional Echocardiography to Improve Initial Diagnosis of Acute Coronary Syndrome in Patients with Chest Pain

   Rochester, Minn.

   The purpose of this study is to see if using two-dimensional speckle tracking echocardiography improves the initial diagnosis of acute coronary syndrome in patients with chest pain who visit the emergency department. 

3. A Study to Evaluate the Use of Lung and intra-abdominal vessels Ultrasond for Intradialytic Complications in Hospitalized Patients on Intermittent Hemodialysis

   Rochester, Minn.

   The purpose of this study is to investigate hospitalized, non-ICU patients undergoing intermittent hemodialysis (HD) to determine:

   • If the combined use of lung and intra-abdominal vessels ultrasound in volume assessment would be better for estimation of dry weight
   • If the changes of the lung ultrasound B line numbers as well as portal venous flow pulsatility and IVC diameters could predict intra-dialytic manifestations and/or complications, such as hypotension, hypertension, tachycardia, and change in oxygen requirements
   • If findings seen with a hand-held scanner are similar to a portable ultrasound scanner

4. New Technologies to Determine Carotid Plaque Vulnerability

   Rochester, Minn.

   Hypothesis: Identification of vulnerable atherosclerotic plaques (with or without neovascularization) using carotid CEUS is an independent predictor of MACE (over clinical risk factors, stress echo wall motion results, and carotid ultrasound two-dimensional speckle tracking strain indices).

   Primary Aims:

   1. Evaluate the diagnostic role of carotid CEUS and two-dimensional speckle tracking strain imaging for detection of carotid plaque:

      • To determine the feasibility and safety of Carotid CEUS and Two-dimensional speckle tracking strain imaging SE .
      • To determine if carotid CEUS and two-dimensional speckle tracking strain imaging findings are associated with coronary angiographic results in those patients undergoing clinically indicated cardiac catheterization.
      • To determine the diagnostic accuracy of CEUS in identifying a vulnerable atherosclerotic plaque and neovascularization compared to carotid MRI, in a subset of patients.

   2. Evaluate the prognostic role of carotid CEUS and two-dimensional speckle tracking strain imaging for prediction of MACE:

      • To determine if plaque identification (with or without neovascularization) on Carotid CEUS SE can improve the overall prediction of MACE over stress echo results alone
      • To determine if Carotid ultrasound two-dimensional speckle tracking strain indices can improve the overall prediction of MACE over stress echo results alone.
      • To determine if the detection of plaque neovascularization by Carotid CEUS is an independent predictor of MACE (over clinical risk factors, stress echo wall motion results, and carotid ultrasound two-dimensional speckle tracking strain indices).

5. Study to Determine if Ultrasound Surface Wave Elastography Can Provide Noninvasive and Accurate Evaluation of Limb Lymphedema

   Rochester, Minn.

   The purpose of this study is to determine if ultrasound surface wave elastography (USWE) produces different recording patterns in healthy and lymphadematous limbs, to establish the relationship between USWE recording values and stages of lymphedema, and to understand the correlation between USWE lymphedema evaluation and other tracking modalities.

    

6. A Study to Evaluate Liver Tumors with Ultrasound Microvessel Imaging and Shear Wave Elastography

   Rochester, Minn.

   The purpose of this study is to investigate the value of ultrasound imaging of tumor microvasculature and stiffness as new biomarkers for evaluation of liver tumor.

7. A Study to Evaluate the GE Ultrasound System Performance

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to evaluate the performance of the investigational GE Ultrasound Systems including image quality, under clinical conditions and to obtain feedback from experienced users.

8. A Motion Compensation Study

   Rochester, Minn.

   The purpose of the study is to assess the Motion Compensation functionality on EPIQ ultrasound system in a clinical environment.

9. A Study to Evaluate Noninvasive Ultrasound Elastography of Kidney and Lung in Assessment of Volume Status in ICU Patients

   Rochester, Minn.

   The primary purpose of this study is to assess the feasibility of performing lung and kidney and lung ultrasound elastography among patients with critical illness from different etiologies that could be associated with volume overload.

10. Mayo Biopsy Marker

    Rochester, Minn.

    This is a Phase 0 clinical trial to evaluate a twinkling biopsy marker (Patent Application Title: Non-Metallic Ultrasound-Detectable Markers Patent Application No.: 62/903,078, Application Type:  Provisional) for ultrasound conspicuity in patients with breast cancer and locally advanced disease involving the axillary lymph nodes.