Informatics and Knowledge Management

A major challenge facing the United States health care system is the sheer volume and complexity of data being generated, stored and applied to individual patients' needs while they receive care.

Within the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, the Informatics and Knowledge Management team addresses these challenges. Informatics and Knowledge Management is a nexus of expertise, building the evidence base to improve health and health care delivery for people everywhere.

Focus areas include:

  • Aggregation
  • Analysis
  • Knowledge curation
  • Knowledge delivery
  • Organization
  • Security
  • Sharing
  • Standardization
  • Storage

Informatics and Knowledge Management combines the most-advanced informatics, data analytics and knowledge management techniques with innovative technology and translates them to address patients' needs. This activity — the intersection of clinical informatics, technology and health care delivery — is applied clinical informatics.

Synergy in science

In 2017, the former Mayo Clinic Office of Information and Knowledge Management was integrated into the Mayo Clinic Kern Center for the Science of Health Care Delivery and given an additional charge. In its expanded role, the team uses information to directly improve human health, leading Mayo Clinic's work in translational informatics.

Translational informatics entails the fusion of computer science, information science and clinical science. This combination enables health care providers to manage, process and effectively present clinical data, information and knowledge. It helps physicians develop innovative practice improvements and patient-centered systems and conduct clinical research.

The consistent, high-quality patient care provided by Mayo Clinic requires not only integrated data but also strategic knowledge management. Informatics and Knowledge Management supports patient care and health care research by effectively leveraging data to generate new knowledge. In turn, this knowledge is used to improve quality and safety, reduce costs, and maintain Mayo's role as a leader in health care innovation.

A clinical knowledge management and delivery program within Informatics and Knowledge Management organizes and manages Mayo Clinic knowledge across the enterprise. Informatics and Knowledge Management provides oversight for the robust infrastructure necessary to drive curation, storage and sophisticated delivery to clinical practice.

The charge of Informatics and Knowledge Management is to:

  • Manage Mayo Clinic knowledge as a strategic asset
  • Create a multidisciplinary knowledge and delivery program at Mayo Clinic to seamlessly deliver information across the converged electronic health record and to various audiences
  • Embed advanced decision-making support at the point of care to raise the quality of care while reducing information overload and burden for providers
  • Accelerate reporting and analytics
  • Realize next-generation capabilities for exchange of information and knowledge within and outside Mayo Clinic

Evolving intelligence

Health care and information technologies around artificial intelligence and machine learning continue to evolve. In 2018, Mayo Clinic announced the establishment of the Office of Augmented Human Intelligence within the center. To enable this new initiative, the Informatics and Knowledge Management team is building new infrastructure and tool sets to complement existing capabilities in data aggregation, standardization, analytics and knowledge management.

Providing core infrastructure for this fast-changing and vital new venue in translational informatics advances the discovery and application of new knowledge to improve patient care. Focusing resources on augmented human intelligence enables Mayo Clinic to build new tools that augment health care providers' ability to handle the large and complex data sets generated in patient care.

Providers will continue to use their deep knowledge of patient care, while using augmented human intelligence tools to augment their decision-making processes. Augmented human intelligence can also provide new insights for care using information buried deep in complex medical records.


Steve G. Peters, M.D.

Mark K. Foley