Research Projects

Investigators in the Evidence-Based Practice Research Program at Mayo Clinic have conducted hundreds of systematic reviews and meta-analyses to support decision-making and clinical practice guidelines by numerous agencies and entities.

These entities include:

  • AABB
  • American Association for the Study of Liver Diseases
  • American College of Chest Physicians
  • American Society of Hematology
  • American Urological Association
  • Centers for Disease Control and Prevention
  • Endocrine Society
  • National Heart, Lung, and Blood Institute
  • Pediatric Endocrine Society
  • Society for Vascular Surgery
  • Undersea and Hyperbaric Medical Society
  • World Health Organization

Systematic review for childhood anxiety

One recent research project within the Evidence-Based Practice Research Program led to a better understanding of treatment options for childhood anxiety.

Childhood anxiety disorders are common, affecting one in eight children. Multiple treatment options are available, including psychotherapy, pharmacotherapy and combined treatment approaches.

Investigators in the Evidence-Based Practice Research Program conducted a systematic review, funded by the Agency for Healthcare Research and Quality, that compared available treatments for childhood anxiety. The results of this systematic review were published in JAMA Pediatrics in 2017.

Tools to support decision-making

Evidence summarized in systematic reviews requires tools to facilitate implementation. The Evidence-Based Practice Research Program developed two tools to improve the care of children with anxiety and to translate the results of the systematic review.

A decision aid (for patients and clinicians) and a health system aid (to provide guidance on resources, costs and logistics of the different treatments) are now available. These aids have been implemented in mental health clinics at Mayo Clinic and are freely available for nationwide use.