Overview

The Evidence-Based Practice Research Program at Mayo Clinic conducts research to evaluate and summarize all available evidence on a particular health care issue.

Investigators in the Evidence-Based Practice Research Program use comprehensive literature searches and advanced qualitative and quantitative synthesis methods. The team's research process encompasses systematic reviews, meta-analysis, meta-regression, meta-narrative synthesis, clinical practice guidelines and methodology research.

Mayo Clinic is one of only 12 institutions in the U.S. currently designated and funded as an evidence-based practice center by the Agency for Healthcare Research and Quality (AHRQ).

These evidence-based practice centers review all relevant scientific literature on a wide spectrum of clinical and health services topics to produce various types of evidence reports. The reports can be used for informing and developing coverage decisions, quality measures, educational materials and tools, clinical practice guidelines, and research agendas. The centers also conduct research on methodology of evidence synthesis.

Evidence synthesis research, such as that conducted by the Evidence-Based Practice Research Program at Mayo Clinic, essentially involves studying research studies. In health care, evidence requires synthesis because a single research study rarely provides all the information needed to make a decision. A stand-alone study can be biased or limited by other factors.

The goals of evidence synthesis are to:

  • Provide the least biased and most precise and applicable results
  • Lead to evidence-based practice and policy decisions
  • Ensure that resources are not wasted pursuing questions that have already been answered
  • Create future research agendas by identifying gaps in knowledge

Read more about the research projects conducted by the Evidence-Based Practice Research Program.

Program leadership

Leadership of the Evidence-Based Practice Research Program at Mayo Clinic includes:

  • Director: M. Hassan Murad, M.D. Dr. Murad, a public health and general preventive medicine specialist, is a professor of medicine at Mayo Clinic College of Medicine and Science in Rochester, Minnesota. As a clinical epidemiologist, Dr. Murad studies how evidence is generated, synthesized, appraised and applied.
  • Associate director: Victor M. Montori, M.D. Dr. Montori, an endocrinologist, is a professor of medicine at Mayo Clinic College of Medicine and Science in Rochester, Minnesota. As a principal investigator in the Knowledge and Evaluation Research Unit, Dr. Montori studies how knowledge is produced, disseminated and taken up in practice, and how this leads to optimal health care delivery and patient outcomes.
  • Associate director: Zhen Wang, Ph.D. Dr. Wang is an associate professor of health services research at Mayo Clinic College of Medicine and Science in Rochester, Minnesota. Dr. Wang studies how current best medical evidence can be used to help patients, health care providers, policy makers and researchers make informed decisions about care and delivery of health services.

Affiliations and resources

Affiliations and resources of the Evidence-Based Practice Research Program include: